Laboratory of Organic Chemistry

Synthetic organic chemistry. Synthesis of organometallic compounds and their study by E.P.R. spectroscopy. Organic synthesis via catalysis. Synthesis of complex compounds with organic ligands. Synthesis of terpenoids.
Development of new methods of peptide synthesis in solution and in solid phase. Synthesis and study of biologically and pharmacologically interesting peptides. Synthesis and study of phospholipases inhibitors. Synthesis and study of fluorogenic substrates for proteases. Inhibitors of metalloproteases: synthesis, conformational analysis, enzymic studies. Synthesis of α-amino acids derivatives. Development of methods for the synthesis of optically active compounds from amino acids.
Studies of free radicals of organic compounds. Reactive oxygen radicals and biological implications. Spin-trapping methods. Risk assessment of carcinogens in the occupational and ambient environment.
Design, synthesis and study of new compounds with anticancer and radioprotective properties. Design, synthesis and study of thiosemicarbazones.

RESEARCH EQUIPMENT AND FACILITIES